Non-Invasive Fractional Flow Reserve Estimation with Coronary Computed Tomography Angiography

Non-Invasive Fractional Flow Reserve Estimation with Coronary Computed Tomography Angiography

Coronary artery disease (CAD) remains a significant cause of morbidity and mortality worldwide [1]. Myocardial ischemia results when myocardial blood flow is insufficient to meet demand; this causes symptoms and affects patient outcome [2]. According to current guidelines for the management of stable CAD, revascularisation should be guided by the presence of myocardial ischaemia. The treatment ...

Coronary Computed Tomography Angiography With Selective Noninvasive Fractional Flow Reserve

Coronary Computed Tomography Angiography With Selective Noninvasive Fractional Flow Reserve

Based on review of available data, the Company may consider the use of noninvasive fractional flow reserve (FFR) following a positive coronary computed tomography angiography (CCTA) to guide decisions about the use of invasive coronary angiography (ICA) in patients with stable chest pain at intermediate risk of coronary artery disease (CAD i.e., suspected or presumed stable ischemic heart disea...

Coronary Computed Tomography Angiography with Selective Noninvasive Fractional Flow Reserve

Fractional flow reserve using coronary computed tomography angiography requires at least 64slice coronary computed tomography angiography and cannot be calculated when images lack sufficient quality (HeartFlow, 2013) (11% to 13% in recent studies; Koo et al, 2011; Min et al, 2012; Nakazato et al, 2013; Nørgaard et al, 2014), e.g., in obese individuals (e.g., body mass index, >35 kg/m2). The pre...

Coronary Computed Tomography Angiography With Selective Noninvasive Fractional Flow Reserve